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Bioinformatics

Mathematical Modelling in Pharmaceutical Development

Project Leader(s): 

Dr. Jack A. Tuszynski , University of Alberta

Project Website: 

http://mitacs-gw.phys.ualberta.ca/mmpd/

Project team: 
Dr. Thoms Hillen, (University of Alberta)
Dr. Gerda de Vries, (University of Alberta)
Dr. Michael Y. Li, (University of Alberta)
Dr. D. Peter Tieleman, (University of Calgary)
Dr. Lukasz Kurgan, (University of Alberta)
Dr. Eric Cytrynbaum, (University of British Columbia)
Dr. Stephane Portet, (University of Manitoba)
Dr. Siv Sivaloganathan, (University of Waterloo)
Dr. Roderick Melnik, (Wilfrid Laurier University)
Non-academic participants: 

Kinetana, Inc. Biomira, Inc. Project CyberCell Inc. Technology Innovations, LLC National Institute for Nanotechnology Cross Cancer Institute McBride Career Group YeTaDel Foundation Oncovista Inc. Howard J. Greenwald P.C. Multimedia Advanced Computational Infrastructure (MACI) Canadian-European Research Initiative on Nanostructure (CERION)

Funding period: 
July 1, 2021 - March 31, 2021
Tags: 
health

Improving Genome Annotation, Molecular Structure and Interaction Prediction: An Algorithmic Study of Biomolecular Functions

Project Leader(s): 

Dr. Anne Condon , University of British Columbia

Project Website: 

http://www.cs.ubc.ca/labs/beta/mitacs/index.htm

Project team: 
Dr. Holger H. Hoos, University of British Columbia
Dr. Ming Li, University of Waterloo
Dr. Irmtraud Meyer, University of British Columbia
Dr. S. Cenk Sahinalp, Simon Fraser University
Dr. Ladislav Stacho, Simon Fraser University
Dr. Peter J. Unrau, Simon Fraser University
Dr. Kaizhong Zhang, University of Western Ontario
Non-academic participants: 

BC Genome Sciences Centre
BC Cancer Researh Centre
IBM Canada
MED BIOGENE Inc
Michael Smith Foundation for Health Research
Zymeworks Inc

Funding period: 
April 1, 2021 - March 31, 2021
Tags: 
health

A Graphical Modeling Framework to Study Complex Dependence Patterns in High-Dimensional Biological Data

Project Leader(s): 

[url=mailto:[email protected]]Dr. Laurent Briollais[/url] , University of Toronto

Project Website: 

http://research.lunenfeld.ca/mprime_Briollais/DEFAULT.ASP

Project team: 
Dr. Gary Bader, University of Toronto
Dr. Adrian Dobra, University of Washington
Dr. Hélène Massam, York University
Dr. Hilmi Ozcelik, Samuel Lunenfeld Research Institute
Non-academic participants: 

[url=http://www.genizon.com/]Genizon Biosciences Inc.[/url]

[url=http://www.wolfram.com/]Wolfram Research[/url]

[url=http://www.ibm.com/ca/en/]IBM[/url]

[url=http://www.tgen.org/]Translational Genomics Research Institute[/url]

Funding period: 
1 April 2021 - 31 March 2021

Graphical models have been one of the most efficient statistical tools used in the last twenty years for the analysis of complex structured high-dimensional data. Graphical models provide a probabilistic framework for making inference and representing the knowledge that we have about these complex structured data. In biological research and more particularly in the emerging -omics disciplines such as genomics, proteomics, metabolomics, transcriptomics, data are often generated from complex high throughput experiments and from complex experimental designs.

Tags: 
health